Mitochondrial Disease Charity - The Lily Foundation
The Lily Foundation logo featuring a butterfly, hearts and an 'x' for a kiss

Fighting mito,
finding hope.

A young mitochondrial disease patient in a wheelchair holding her hands to her mouth A young mitochondrial disease patient in a wheelchair holding her hands to her mouth

Christmas Appeal 2025

It takes courage to face mitochondrial disease. It takes compassion to help. Will you?

Donate today

Every other day in the UK, a baby is born who may develop serious mitochondrial disease

smiley young boy with mito, walking down a sunny lane with the assistance of a walking frame

Mitochondrial disease, or ‘mito’, is a rare, complex and difficult-to-diagnose genetic disorder that affects people in very different ways. It can affect any organ at any age, and often occurs in babies and young children. There is currently no cure, but we’re working hard to change that, and are the largest charitable funder of mitochondrial research in Europe.

Mitochondrial dysfunction has been identified as a key factor in other more common diseases including dementia, Parkinson's disease, epilepsy and cancer. The research we fund and support not only holds promise for individuals with mitochondrial disorders, but has the potential to benefit millions of others too.

That’s why, despite being a little-known disease, mitochondrial disease could be the key to some of the most important medical breakthroughs of our time.

Find out more

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What does it take to live with mitochondrial disease?

This Christmas, we want to show you just what it takes to live with mitochondrial disease.

Meet Harry, Mandy, Katie, Tom and Leia, all real people, living with mito every day. Leia and her family show incredible courage as they fight her incurable condition. Harry and his mum Mandy have hope and belief for the future. They all have what it takes – but they can’t do it alone.

With your support, The Lily Foundation can keep providing care for families like these, funding vital research and finding hope where it’s needed most. Do you have what it takes to help us fight mito? Donate this Christmas to make a difference.

Our impact

  • £11m

    Raised
    since 2007

  • 1500

    Families
    supported

  • £200k

    Donated
    to patients

  • 23

    Research projects
    funded

Latest news

A seasonal singalong in support of The Lily Foundation

Every December, Sloane Square’s Holy Trinity Church sparkles with light, music and festive cheer as Goldsmiths Choral Union (GCU) hosts its much-loved Christmas Carol Concert. A cherished part of London’s musical calendar, in recent years it’s also become a wonderful opportunity for us to raise awareness and funds.

It takes belief to live with mitochondrial disease

For Harry and his mum, their belief has been tested again and again. Harry lives with MERRF, but it took nearly 20 years for his syndrome to be correctly identified. We spoke to them about an ordeal all too common for adults with mitochondrial disease – the long and winding road to a diagnosis – and how they’ve learnt to live with positivity and belief in the face of an uncertain future.

Our Christmas shop is open!

Visit our Christmas shop where you’ll find everything from Lily-branded clothing to unique gifts and stocking fillers. When you buy from The Lily Foundation, not only will your gifts bring joy to your loved ones, but they’ll also help fight mitochondrial disease and find hope for everyone affected.